Thomas J Kornecook Selected Research

AMG8379

1/2017

Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7.

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Thomas J Kornecook Research Topics

Disease

4	Pain (Aches) 01/2019 - 01/2017
2	Chronic Pain 01/2019 - 01/2017
2	Pruritus (Itching) 11/2018 - 01/2017
1	Burns 01/2017
1	Hyperalgesia 01/2017
1	Obesity 04/2011
1	Memory Disorders (Memory Loss) 04/2011
1	Mental Disorders (Mental Disorder) 04/2011

Drug/Important Bio-Agent (IBA)

4	Voltage-Gated Sodium ChannelsIBA 01/2019 - 01/2017
3	Histamine (Histamine Dihydrochloride)FDA Link 11/2018 - 01/2017
2	Pharmaceutical PreparationsIBA 01/2019 - 04/2011
1	Peptides (Polypeptides)IBA 11/2018
1	Spider Venoms (Venom, Spider)IBA 11/2018
1	SulfonamidesIBA 01/2017
1	Capsaicin (Zostrix)FDA Link 01/2017
1	Formaldehyde (Formol)FDA Link 01/2017
1	BenzoxazinesIBA 01/2017
1	SodiumIBA 01/2017
1	AMG8379IBA 01/2017
1	3- (1- (1- ((4- chlorophenyl)(3- (5- oxo- 4,5- dihydro- 1,3,4- oxadiazol- 2- yl)phenyl)methyl)azetidin- 3- yl)- 2- fluoro- 2- methylpropyl)- 5- fluorobenzonitrileIBA 04/2011
1	Scopolamine (Hyoscine)FDA Link 04/2011
1	Cannabinoid Receptors (Cannabinoid Receptor)IBA 04/2011
1	CB1 Cannabinoid Receptor (CB1 Receptor)IBA 04/2011

Therapy/Procedure

2	Therapeutics 11/2018 - 01/2017